vx-809

$250.00$7,000.00

Alternate Name/Synonyms3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid; Lumacaftor
AppearanceWhite to off-white solid
CAS Number936727-05-8
Molecular FormulaC₂₄H₁₈F₂N₂O₅
Molecular Weight452.41
SolubilityDMSO (>90 mg/ml)
Storage Temp.-20 ̊C
Shipping Conditionsgel pack
HandlingProtect from air and light
SMILESCC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O
InChiInChI=1S/C24H18F2N2O5/c1-13-5-8-19(27-20(13)14-3-2-4-15(11-14)21(29)30)28-22(31)23(9-10-23)16-6-7-17-18(12-16)33-24(25,26)32-17/h2-8,11-12H,9-10H2,1H3,(H,29,30)(H,27,28,31)
InChi KeyUFSKUSARDNFIRC-UHFFFAOYSA-N
PubChem CID16678941
USAGEFor Research Use Only! Not For Use in Humans.
WEIGHT 1g 5g 10g 25g 50g 100g
PRICE $250.00
(per gram)
$170.00
(per gram)
$150.00
(per gram)
$100.00
(per gram)
$80.00
(per gram)
$70.00
(per gram)

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Description

VX-809 is a novel CFTR corrector that modulates the folding and trafficking of CFTR protein. VX-809 stabilizes an N-terminal domain in CFTR that contains only MSD1 (membrane-spanning domain 1) and efficaciously restores function to CFTR forms that have mi
Item Code: LF-0028

Additional information

WEIGHT

1g, 5g, 10g, 25g, 50g, 100g

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